原 著

犬におけるアシュネル眼球圧迫試験

川 崎 安 亮    森 山 良 人

鹿児島大学農学部(〒890-0065 鹿児島市郡元1-21-24)

(2003年8月15日受付・2003年10月31日受理)

要     約
  アシュネル眼球圧迫試験における心拍変動(HRV)を健常な成犬7頭(雑種5頭,イングリッシュポインター2頭)で検討した.眼球圧迫は95g/cm2,20秒間とした.HRVの指標には,心電図のRR間隔(RRI)の平均値,標準偏差(SDR-R),変動係数(CVR-R)および瞬時心拍数(IHR)を用いた.RRI時系列(RRITS)は13点単純移動平均法を用いて,短期変動時系列(STTS)と長期変動時系列(LTTS)に分離した.STTSと呼吸周期の平均周期は有意な正の相関(r=0.974)を示したので,呼吸性洞性不整脈(RSA)はSTTSに反映されると考えられる.RRITSのSDR-RとCVR-R,およびLTTSのCVR-Rは眼球圧迫により有意(P<0.05)に上昇した.したがって,生理的なRSAが顕著な犬でも,眼球圧迫による副交感神経の緊張度亢進はCVR-Rに反映されると考えられる.アシュネル眼球圧迫試験の生理的な最大徐脈は,眼球圧迫前1分間の平均IHRに対して−10.4±3.4拍/分(−13.1±5.0%),95%信頼区間は−12.9〜−7.8拍/分(−16.8〜−9.4%)であり,17%以上の徐脈が犬における本試験の反射亢進の暫定的基準となると考えられる.
―キーワード:徐脈,犬,心拍変動,眼球心臓反射,RR間隔.

-------------------日獣会誌 57,186〜191(2004)


Aschner Eyeball-pressure Test for Dogs

Yasuaki KAWASAKI*† and Yoshito MORIYAMA

Department of Veterinary Physiology, Faculty of Agriculture, Kagoshima University, 1-21-24
Korimoto, Kagoshima, 890-0065, Japan

SUMMARY

 Heart-rate variability (HRV) induced by the Aschner eyeball-pressure test was analyzed in 7 adult dogs. Ocular compression (OC) used was 95 g/cm2, and duration was 20 seconds. Average, standard deviation (SDR-R), coefficient of variance (CVR-R) of the RR interval (RRI) of electrocardiogram, and beat-to-beat instantaneous heart rates (IHR) were used as indices for HRV. The RRI time series (RRITS) was divided into short-term (STTS) and long-term time series (LTTS) by means of a 13-point simple moving average method. The mean cycle of STTS correlated closely with that of the respiration curve (r=0.974), indicating that the STTS reflects respiratory sinus arrhythmia (RSA). No HRV variables in the STTS changed significantly, but SDR-R and CVR-R in the RRITS and CVR-R in the LTTS increased significantly (P<0.05) as a result of OC. Therefore, OC-induced parasympathotonia may reflect on CVR-R of the RRI in dogs with RSA. The maximum physiological bradycardia caused by OC was −10.4±3.4 beats/min (−13.1±5.0%) compared to the mean IHR one minute before compression. On the basis of the 95% confidence interval of bradycardia (−12.9〜−7.8 beats/min) (−16.8〜−9.4%), we concluded that the hyper-reflexia of this test as applied to dogs represents a drop in heart rate of 17% or more.
―Key words : bradycardia, dog, heart-rate variability, oculo-cardiac reflex, RR interval.
 Correspondence to : Yasuaki KAWASAKI (Department of Veterinary Physiology, Faculty of Agriculture, Kagoshima University)
1-21-24 Korimoto, Kagoshima,
890-0065, Japan
TEL・FAX 099-285-8715


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J. Jpn. Vet. Med. Assoc., 57, 186〜191 (2004)