要 約
エリスロマイシンの気道における線毛粘液輸送機能改善作用に着目し,子牛の慢性呼吸器疾患に対する治療効果について検討した.3〜7カ月齢の慢性呼吸器疾患を呈した黒毛和種子牛10頭について,試験群8頭にはエリスロマイシンを30〜60日間経口投与し,対照群2頭にはアモキシシリンを10または14日間経口投与した.エリスロマイシン長期投与により,一般症状の軽減がみられたが,特に強い副作用は認められなかった.
―キーワード:子牛,慢性呼吸器疾患,エリスロマイシン,長期投与.
--------------------日獣会誌 54,757〜760(2001)
Long-term Prescription of Erythromycin for Chronic Respiratory Disease in Calves
Daishi OKADA*†, Tadamasa HASHIMOTO, Nobue SUMI,
Satoru NISHIZAKI and Kazuhiko TAHARA
*Awaji Nucleus Veterinary Clinical Center, Hyogo P.F.A.M.A.A.,
784-2 Miyanohara, Aigo, Sumoto 656-2126, Japan
SUMMARY
Specific attention was devoted to using erythromycin to improve the mucus-cilium
clearance function in the respiratory tract. The effects of long-term treatment with erythromycin on
chronic respiratory diseases in calves were examined. Subjects of examination were 10 Japanese black
calves aged 3 to 7 days and suffering from chronic respiratory disease. Erythromycin was administered
to the 8 calves in the experimental group for from 30 to 60 days. Amoxicillin was administered to the
2 calves in the control group for from 10 to 14 days. Long-term erythromycin prescription was found to
improve clinical signs effectively. Long-term usage of the drug produced no side effects.
―Key words : calf, chronic respiratory disease, erythromycin, long-term usage.
† Correspondence to : |
Daishi OKADA (Awaji Nucleus Veterinary Clinical Center, Hyogo P.F.A.M.A.A.)
784-2 Miyanohara, Aigo, Sumoto 656-2126, Japan
TEL 0799-28-1650 FAX 0799-28-1655
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-------------------- J. Jpn. Vet. Med. Assoc., 54, 903〜908 (2001) |