発育不良の黒毛和種牛における甲状腺機能

北川 均1)  鬼頭克也1)  伊藤哲郎1)  大場恵典1)  金沢金吾2)
長谷川弘美3)  川合良郎4)  古橋 武5)  佐々木榮英1)

1) 岐阜大学農学部(〒501-1193 岐阜市柳戸1-1)
2) 明宝村家畜診療所(〒501-4307 岐阜県郡上郡明宝村二間手222-1)
3) 八幡町役場農林課(〒501-4297 岐阜県郡上郡八幡町島谷228)
4) 大和町農業振興対策センター(〒501-4612 岐阜県郡上郡大和町剣82-1)
5) 高鷲村畜産指導所(〒501-5303 岐阜県郡上郡高鷲村大鷲814-2)

(2000年1月28日受付・2000年4月26日受理)

要     約
 正常体型の黒毛和種発育不良牛8頭について,甲状腺機能を検討した.発育不良牛は生時より異常症状を認めなかったが,3〜4カ月齢から発育が遅延した.食欲と活動性が低下していた3頭では,血清基礎総triiodothyronine(T3)濃度と基礎総thyroxine(T4)濃度は低値であった.thyrotrophin-releasing hormone(TRH)刺激により2頭でT4が上昇したが,1頭では低値を維持した.正常食欲と活動性を示した5頭では,T3は1頭で正常,4頭で低値であり,T4は1頭で正常,2頭で中等度に低値,2頭で検出限界以下であった.TRH刺激後,5頭ともT4が上昇した.これら8頭の発育不良牛における低甲状腺ホルモン濃度は正常甲状腺疾患症候群(euthyroid sick syndrome)であることが示唆された.
―キーワード:正常甲状腺疾患症候群,発育不良,黒毛和種牛,甲状腺機能.
--------------------日獣会誌 53,735〜739(2000)


hyroid Function in Growth-retarded Japanese Black Cattle

Hitoshi KITAGAWA*, Katsuya KITO, Tetsuro ITO, Yasunori OBA, Kingo KANAZAWA, Hiromi HASEGAWA, Yoshiro KAWAI, Takeshi FURUHASHI and Yoshihide SASAKI

*Faculty of Agriculture, Gifu University, 1h1 Yanagido, Gifu 501h1193, Japan

SUMMARY
  Clinical findings and thyroid function were examined in 8 growth-retarded Japanese Black cattle. Until about 3 or 4 months of age, the animals had grown normally and had had normal appetites. At initial examination (3 to 13 months of age), however, their bodies were very small, though normally proportioned. Laboratory tests revealed no characteristic findings. Three of the cattle had poor appetites and were largely inactive. Their basal serum total triiodothyronine (T3) concentrations and serum total thyroxine (T4) concentrations were low. Thyrotrophin-releasing hormone (TRH) stimulating tests showed serum total T4 concentrations to have increased in 2 animals and to have remained at a low level in one. Of five animals demonstrating normal appetite and activity, serum total T4 concentrations were normal in 1, moderately low in 2, and very low in 2. These concentrationsincreased in all 5 after TRH stimulation. These 8 growth-retarded animals may have been suffering from the euthyroid sick syndrome.
―Key words : euthyroid sick syndrome, growth retardation, Japanese Black cattle, thyroid function.
 J. Jpn. Vet. Med. Assoc., 53, 735〜739 (2000)