帝王切開術によるSPF豚作出へのイソフルレン麻酔の応用

森岡秀就    坂口  実

富山県畜産試験場(〒939-2622 富山県婦負郡婦中町千里前山1)

(1999年3月5日受付・1999年7月5日受理)

要     約

 帝王切開術によるSPF豚作出へのイソフルレン麻酔の応用について検討した.硫酸アトロピン(0.05mg/kg)およびアザペロン(2mg/kg)の投与後,笑気―酸素―イソフルレンによる吸入麻酔を行い,あわせて塩酸プロカインで局所浸潤麻酔した.イソフルレンの濃度は,痛覚反応を経時的に観察し,安全な手術が可能な最低濃度にまで下げて維持した.すなわち,吸入麻酔導入後4〜7分でイソフルレン濃度を4%から0.5%にまで下げ,0.5%で維持した.その結果,非妊娠豚でのMACを指標とした導入から胎子摘出終了までのイソフルレン投与量は31.4±4.1MAC・minとなり,95.8±6.9%の高い子豚蘇生率が得られ,母豚に対する安全性も確認された.
―キーワード:帝王切開術,吸入麻酔,イソフルレン,SPF豚.

--------------------日獣会誌 52,768〜771(1999)


Isoflurane Anesthesia during Cesarean-section Delivery of SPF Pigs

Hidenari MORIOKA and Minoru SAKAGUCHI

Toyama Prefectural Livestock Experiment Station, 1 Chisato-Maeyama, Fuchu-machi, Nei-gun, Toyama 939-2622, Japan

SUMMARY

 Isoflurane anesthesia was evaluated for use in cesarean-section delivery of specific-pathogen-free (SPF) pigs. Pregnant gilts were premedicated with atropine sulfate(0.05 mg/kg) and azaperone (2 mg/kg) and then anesthetized by inhalation of 4% isoflurane delivered in a mixed gas (N2O : O2 = 1 : 2) through a face mask. After anesthetization, local infiltration anesthesia with procaine hydrochloride was performed at the incision site. While nociceptive reactions were being monitored at 4 to 7 minutes after anesthetization, isoflurane concentration was reduced to 0.5% and maintained at this level until completion of delivery. A small amount of isoflurane (31.4±4.1 MAC・min) resulted in high yields of live piglets (95.8±6.9%) with no notable adverse effects on the gilts.
―Key words : cesarean section, inhalation anesthesia, isoflurane, specific-pathogen-free pig.

--------------------J. Jpn. Vet. Med. Assoc., 52, 768〜771 (1999)