1)なかはら動物病院(〒509-0203 可児市下恵土5911-1) 2)大阪府立大学農学部(〒599-8531 堺市学園町1-1) |
(1997年8月6日受付・1998年8月20日受理)
元気消失,食欲廃絶を主訴としたペルシャ猫(雄,11歳)において重度の非再生性貧血,好中球増加症と単球増加症が認められ,末梢血に芽球と前単球出現がみられた.血清中のネコ白血病ウイルス抗原およびネコ免疫不全ウイルス抗体は陽性で,直接クームテストは陽性であった.骨髄では芽球の著しい増加と,赤芽球系細胞の著しい減少がみられ,芽球はペルオキシダーゼ陽性で,非特異的エステラーゼ陰性であった.形態的に末梢血および骨髄でみられた未熟細胞は顆粒球形および単球系の前駆細胞と考えられ,本例は非特異的エステラーゼ陰性のまれな急性骨髄単球性白血病(M4)と診断された. --------------------日獣会誌 52,105〜108(1999)
A Feline Case of Acute Myelomonocytic Leukemia (M4)Toru OSAMURA*, Kimihiko NAKAHARA and Tadashi MIYAMOTO
SUMMARY An 11-year-old male Persian cat with depression and anorexia showed severe nonregenerative anemia,
neutrophilia, and monocytosis, and a number of blast cells and promonocytes appeared in the peripheral
blood. Feline leukemia virus antigen and antibody to feline immunodeficiency virus were detected in serum,
which was positive for direct Coombs' test. The bone marrow had an increased number of blast cells and
marked depletion of erythroid precursors. The blast cells were positive for peroxidase while negative
for nonspecific esterase. The immature cells in the peripheral blood and bone marrow were morphologically
suggested to be precursors of either granulocytes or monocytes. The case was diagnosed as acute myelomonocytic
leukemia (M4), that was negative for nonspecific esterase and rare in cats. --------------------J. Jpn. Vet. Med. Assoc., 52, 105〜108(1999) |